SCHEMBL8159754

SCHEMBL8159754

C=CCCCCCCC(C)=C(C)[SiH3]

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
ABCC4 O15439 1/20 0.48
ALDH1A1 P00352 4/20 0.47
LMNA P02545 2/20 0.47
TSHR P16473 2/20 0.44
CYP3A4 P08684 3/20 0.38
USP2 O75604 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
RECQL P46063 1/20 0.38
LPAR3 Q9UBY5 2/20 0.34
LPAR2 Q9HBW0 1/20 0.34
HPGD P15428 1/20 0.33
TRPA1 O75762 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8075844 0.79 MAPT (0.48) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL8118845 0.77 MAPT (0.56) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL5184876 0.77 MAPT (0.56) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL8205469 0.77 MAPT (0.56) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL23014107 0.75 MAPT (0.54) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL23014106 0.75 MAPT (0.54) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL774740 0.75 MAPT (0.54) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL25492822 0.75 MAPT (0.54) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL20863642 0.75 MAPT (0.54) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL8413864 0.75 MAPT (0.54) MAPTABCC4ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3768686-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies, LLC (US) 2021-01-27 EP claimed
EP-3768687-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP claimed
US-20210002308-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-07 US claimed
US-20210002315-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-07 US claimed
CN-112074525-A Silicon-terminated organometallic compounds and methods for making the same 陶氏环球技术有限责任公司 2020-12-11 CN claimed
CN-112004818-A Silicon-terminated organometallic compounds and methods of making the same 陶氏环球技术有限责任公司 2020-11-27 CN claimed
WO-2019182983-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO claimed
WO-2019182988-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO claimed
EP-3768686-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies, LLC (US) 2021-01-27 EP disclosed
EP-3768733-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP disclosed
EP-3768687-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP disclosed
US-20210017311-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2021-01-21 US disclosed
US-20210002315-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-07 US disclosed
US-20210002308-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-07 US disclosed
WO-2019182983-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO disclosed
WO-2019182988-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO disclosed
WO-2019182993-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO disclosed
EP-0620258-B1 Radiation-curable poly(alpha-olefin) adhesives containing pendant olefinic functionality MINNESOTA MINING & MFG (US) 2000-01-05 EP disclosed
US-5407970-A Peel adhesion, cohesive strength at elevated temperatures MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-18 US disclosed
EP-0620258-A2 Radiation-curable poly(alpha-olefin) adhesives containing pendant olefinic functionality MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002308-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME SCAMP2, SOD1, SCLY MAPT 4501/4885ABCC4 1471/4885ALDH1A1 1828/4885
US-20210002315-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME SIK1, SIK2, MCM7 MAPT 1981/4885ABCC4 2005/4885ALDH1A1 3276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.