Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160987 | 0.98 | LMNA (0.33) | LMNA | |
| SCHEMBL301789 | 0.91 | LMNA (0.31) | LMNA | |
| SCHEMBL4453998 | 0.86 | LMNA (0.35) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8670101 | 0.83 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8668872 | 0.83 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8667708 | 0.83 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8664730 | 0.83 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL819274 | 0.83 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL819089 | 0.83 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8666445 | 0.83 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133189-A | POLYMRIZATION CATALYST CONSISTS OF (1) A SOLILD CATALYST-REACTION PRODUCT OF TETRAVALENT TITANIUM AND ORGANOMAGNESIUM COMPOUND FORMED BY REACTING ORGANOSILICON AND ORGANOMAGENSIUM COMPOUNDS, (2) ORGANOALUMINUM COMPOUND, (3) ORGANOSILICON | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-17 | — | — | US | claimed |
| EP-0748820-B1 | Alpha-olefin polymerization catalyst and process for producing alpha-olefin polymer | SUMITOMO CHEMICAL CO (JP) | 2000-11-29 | — | — | EP | disclosed |
| US-6133189-A | POLYMRIZATION CATALYST CONSISTS OF (1) A SOLILD CATALYST-REACTION PRODUCT OF TETRAVALENT TITANIUM AND ORGANOMAGNESIUM COMPOUND FORMED BY REACTING ORGANOSILICON AND ORGANOMAGENSIUM COMPOUNDS, (2) ORGANOALUMINUM COMPOUND, (3) ORGANOSILICON | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-0748820-A1 | Alpha-olefin polymerization catalyst and process for producing alpha-olefin polymer | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-12-18 | — | — | EP | disclosed |