SCHEMBL8160987

SCHEMBL8160987

CCCCC[Si](OC)(OC)C(C)(C)CC

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8160258 0.98 LMNA (0.36) LMNA
SCHEMBL301789 0.93 LMNA (0.31) LMNA
SCHEMBL301706 0.84 ALDH1A1 (0.32)
SCHEMBL4453998 0.83 LMNA (0.35) LMNA
SCHEMBL819775 0.82 LMNA (0.35) LMNA
SCHEMBL8165955 0.81
SCHEMBL8670101 0.80 LMNA (0.38) LMNA
SCHEMBL819274 0.80 LMNA (0.38) LMNA
SCHEMBL8666445 0.80 LMNA (0.38) LMNA
SCHEMBL8667708 0.80 LMNA (0.38) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6133189-A POLYMRIZATION CATALYST CONSISTS OF (1) A SOLILD CATALYST-REACTION PRODUCT OF TETRAVALENT TITANIUM AND ORGANOMAGNESIUM COMPOUND FORMED BY REACTING ORGANOSILICON AND ORGANOMAGENSIUM COMPOUNDS, (2) ORGANOALUMINUM COMPOUND, (3) ORGANOSILICON SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-17 US claimed
EP-0748820-B1 Alpha-olefin polymerization catalyst and process for producing alpha-olefin polymer SUMITOMO CHEMICAL CO (JP) 2000-11-29 EP disclosed
US-6133189-A POLYMRIZATION CATALYST CONSISTS OF (1) A SOLILD CATALYST-REACTION PRODUCT OF TETRAVALENT TITANIUM AND ORGANOMAGNESIUM COMPOUND FORMED BY REACTING ORGANOSILICON AND ORGANOMAGENSIUM COMPOUNDS, (2) ORGANOALUMINUM COMPOUND, (3) ORGANOSILICON SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-17 US disclosed
EP-0748820-A1 Alpha-olefin polymerization catalyst and process for producing alpha-olefin polymer SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-12-18 EP disclosed