Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 17/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 14/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.46 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.46 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154357 | 0.97 | L3MBTL3 (0.52) | L3MBTL3L3MBTL1GRM5MBTD1TP53BP1 | |
| SCHEMBL8167234 | 0.88 | GRM5 (0.53) | L3MBTL3L3MBTL1GRM5MBTD1TP53BP1 | |
| SCHEMBL24722046 | 0.84 | L3MBTL3 (0.67) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL3639179 | 0.84 | L3MBTL3 (0.73) | L3MBTL3L3MBTL1GRM5MBTD1TP53BP1 | |
| SCHEMBL8163323 | 0.83 | GRM5 (0.69) | L3MBTL1GRM5 | |
| SCHEMBL8167410 | 0.82 | KDM4E (0.43) | L3MBTL3L3MBTL1GRM5MBTD1TP53BP1 | |
| SCHEMBL3637708 | 0.81 | L3MBTL3 (0.76) | L3MBTL3L3MBTL1GRM5MBTD1TP53BP1 | |
| SCHEMBL8154173 | 0.80 | GRM5 (0.48) | GRM5 | |
| SCHEMBL8161856 | 0.80 | GRM5 (0.50) | GRM5 | |
| SCHEMBL8161960 | 0.79 | GRM5 (0.47) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151184-A1 | BENZAMIDE MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME | VANDERBILT UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |