Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.76 |
| ▸ | APP | P05067 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162868 | 1.00 | ALOX5 (0.76) | ALOX5APPKDM4EALDH1A1AKR1C3 | |
| SCHEMBL8162302 | 0.96 | ALOX5 (0.76) | ALOX5APPKDM4EALDH1A1AKR1C3 | |
| SCHEMBL8162304 | 0.96 | ALOX5 (0.76) | ALOX5APPKDM4EALDH1A1AKR1C3 | |
| SCHEMBL8168383 | 0.93 | ALOX5 (0.68) | ALOX5APPKDM4EALDH1A1AKR1C3 | |
| SCHEMBL8168381 | 0.93 | ALOX5 (0.68) | ALOX5APPKDM4EALDH1A1AKR1C3 | |
| SCHEMBL29489703 | 0.92 | ALOX5 (0.84) | ALOX5APPKDM4EALDH1A1AKR1C3 | |
| SCHEMBL29489695 | 0.86 | ALOX5 (0.83) | ALOX5APPKDM4EALDH1A1AKR1C3 | |
| SCHEMBL30219096 | 0.86 | ALOX5 (1.00) | ALOX5APPKDM4EALDH1A1LMNA | |
| SCHEMBL9534542 | 0.86 | ALOX5 (0.83) | ALOX5APPKDM4EALDH1A1AKR1C3 | |
| SCHEMBL9534555 | 0.86 | ALOX5 (0.83) | ALOX5APPKDM4EALDH1A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974573-A1 | PHENYLPROPENONE COMPOUNDS AND MEDICINES CONTAINING THE SAME | Kabushiki Kaisha Yakult Honsha (JP) | 2000-01-26 | — | — | EP | disclosed |