Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.76 |
| ▸ | APP | P05067 | 9/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162304 | 1.00 | ALOX5 (0.76) | ALOX5APPKDM4EALDH1A1HPGD | |
| SCHEMBL8162874 | 0.96 | ALOX5 (0.76) | ALOX5APPKDM4EALDH1A1HPGD | |
| SCHEMBL8162868 | 0.96 | ALOX5 (0.76) | ALOX5APPKDM4EALDH1A1HPGD | |
| SCHEMBL8168381 | 0.93 | ALOX5 (0.68) | ALOX5APPKDM4EALDH1A1HPGD | |
| SCHEMBL8168383 | 0.93 | ALOX5 (0.68) | ALOX5APPKDM4EALDH1A1HPGD | |
| SCHEMBL29489703 | 0.92 | ALOX5 (0.84) | ALOX5APPKDM4EALDH1A1HPGD | |
| SCHEMBL10826185 | 0.90 | APP (0.66) | ALOX5APPKDM4EALDH1A1HPGD | |
| SCHEMBL10826184 | 0.90 | APP (0.66) | ALOX5APPKDM4EALDH1A1HPGD | |
| SCHEMBL29489692 | 0.87 | ALOX5 (0.76) | ALOX5APPKDM4EALDH1A1HPGD | |
| SCHEMBL30219096 | 0.86 | ALOX5 (1.00) | ALOX5APPKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974573-A1 | PHENYLPROPENONE COMPOUNDS AND MEDICINES CONTAINING THE SAME | Kabushiki Kaisha Yakult Honsha (JP) | 2000-01-26 | — | — | EP | disclosed |