SCHEMBL816366

SCHEMBL816366

CCCCC[CH][Si](C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.43
THRB P10828 1/20 0.39
FAAH O00519 2/20 0.39
TRPV1 Q8NER1 2/20 0.39
DNM1 Q05193 3/20 0.36
ALDH1A1 P00352 2/20 0.36
EP300 Q09472 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL817904 0.97 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL816732 0.97 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL816800 0.97 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL820200 0.97 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL816249 0.97 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL815164 0.97 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL816060 0.97 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL816295 0.97 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL817572 0.97 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL815837 0.97 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
US-20230110603-A1 3-ALKOXYBENZAMIDE DERIVATIVE, AND PEST CONTROL AGENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2023-04-13 US disclosed
EP-4098650-A1 3-ALKOXY BENZOIC ACID AMIDE DERIVATIVE, AND PEST CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2022-12-07 EP disclosed
CN-115052856-A 3-alkoxybenzamide derivative and pest control agent 组合化学工业株式会社 2022-09-13 CN disclosed
WO-2021153720-A1 3-ALKOXY BENZOIC ACID AMIDE DERIVATIVE, AND PEST CONTROL AGENT クミアイ化学工業株式会社 2021-08-05 WO disclosed
CN-105492374-B Synthesis and hydrogen storage performance of manganese hydride 南威尔士大学商业服务有限公司 2019-08-30 CN disclosed
EP-1960411-B1 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2016-08-31 EP disclosed
US-9163046-B2 Process for producing substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-10-20 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed
US-20040015002-A1 Novel organometallic compound having high metathesis activity and method for preparation thereof, metathesis reaction catalyst comprising the compound, method of polymerization using the catalyst, and polymer produced by the method of polymerization SEKISUI CHEMICAL CO., LTD. (JP) 2004-01-22 US disclosed
EP-1334977-A1 NOVEL ORGANOMETALLIC COMPOUND HAVING HIGH METATHESIS ACTIVITY AND METHOD FOR PREPARATION THEREOF, METATHESIS REACTION CATALYST COMPRISING THE COMPOUND, METHOD OF POLYMERIZATION USING THE CATALYST, AND POLYMER PRODUCED BY THE METHOD OF POLYMERIZATION SEKISUI CHEMICAL CO., LTD. (JP) 2003-08-13 EP disclosed
WO-2003018521-A1 SUBSTITUTED ALKENE DIOLS ISIS INNOVATION LIMITED (GB) 2003-03-06 WO disclosed
US-6162799-A Pesticidal compounds BTG INTERNATIONAL LIMITED (GB) 2000-12-19 US disclosed
EP-0850239-A1 PESTICIDAL COMPOUNDS BTG INTERNATIONAL LIMITED (GB) 1998-07-01 EP disclosed
WO-1997002271-A1 PESTICIDAL COMPOUNDS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1997-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040015002-A1 Novel organometallic compound having high metathesis activity and method for preparation thereof, metathesis reaction catalyst comprising the compound, method of polymerization using the catalyst, and polymer produced by the method of polymerization PPOX, COASY, MSMO1 TSHR 4684/4885THRB 4837/4885FAAH 3111/4885
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 TSHR 4680/4885THRB 3757/4885FAAH 4301/4885
US-20230110603-A1 3-ALKOXYBENZAMIDE DERIVATIVE, AND PEST CONTROL AGENT CBR3, ALK, BRS3 TSHR 1118/4885THRB 1225/4885FAAH 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.