SCHEMBL8164342

SCHEMBL8164342

CC1(C)c2cc(O)ccc2Oc2ccc(O)cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
XDH P47989 1/20 0.43
GAA P10253 3/20 0.41
OPRM1 P35372 6/20 0.40
MAPT P10636 4/20 0.40
OPRK1 P41145 2/20 0.40
CYP3A4 P08684 1/20 0.39
CNR2 P34972 1/20 0.39
MEN1 O00255 2/20 0.37
RECQL P46063 2/20 0.37
KMT2A Q03164 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
HPGD P15428 1/20 0.37
CYP2C19 P33261 1/20 0.37
HTT P42858 1/20 0.37
BLM P54132 1/20 0.37
SMAD3 P84022 1/20 0.37
PRMT1 Q99873 1/20 0.37
ACE2 Q9BYF1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8163250 0.92 CNR2 (0.48) PTGS1PTGS2XDHGAAOPRM1
SCHEMBL2348300 0.83 CNR2 (0.53) PTGS1PTGS2XDHGAAMAPT
SCHEMBL23861417 0.82 PTGS1 (0.40) PTGS1PTGS2XDHGAAOPRM1
SCHEMBL3694882 0.80 PTGS1 (0.42) PTGS1PTGS2XDHGAAOPRM1
SCHEMBL8671289 0.79 OPRM1 (0.34) PTGS1PTGS2XDHGAAOPRM1
SCHEMBL23861359 0.77 PTGS1 (0.37) PTGS1PTGS2XDHGAAOPRM1
SCHEMBL23861406 0.77 HPGD (0.40) PTGS1PTGS2XDHGAAOPRM1
SCHEMBL6509446 0.76 MAPT (0.38) GAAMAPTCYP3A4MEN1RECQL
SCHEMBL30956355 0.75 PDK2 (0.46) OPRM1OPRK1KDM4EALDH1A1CA1
SCHEMBL2123476 0.75 PDK2 (0.46) OPRM1OPRK1KDM4EALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719813-B1 Copolycarbonate GEN ELECTRIC (US) 2000-10-18 EP disclosed
US-5670605-A MELT COPOLYMERIZATION DIHYDROXYAROMATIC COMPOUNDS TO FORM POLYMERS GENERAL ELECTRIC COMPANY (US) 1997-09-23 US disclosed
CN-1132216-A Copolycarbonate, copolycarbonate composition, and method for their manufacture GEN ELECTRIC (US) 1996-10-02 CN disclosed
EP-0719813-A2 Copolycarbonate GENERAL ELECTRIC COMPANY (US) 1996-07-03 EP disclosed