SCHEMBL6509446

SCHEMBL6509446

Cc1ccc2c(c1)C(C)(C)c1cc(C)ccc1O2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
THRB P10828 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 2/20 0.38
HTT P42858 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
RECQL P46063 1/20 0.38
GAA P10253 2/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MMP12 P39900 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
HTR2C P28335 2/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
AKR1B1 P15121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2756742 0.92 MAPT (0.34) MAPTTHRBTDP1MEN1HTT
SCHEMBL9188443 0.90 GAA (0.38) MAPTTHRBTDP1MEN1HTT
SCHEMBL16426146 0.89 AHR (0.45) MAPTTHRBTDP1MEN1HTT
SCHEMBL17371259 0.84 GAA (0.39) MAPTTHRBTDP1MEN1HTT
SCHEMBL7521829 0.82 LMNA (0.36) MAPTTHRBTDP1MEN1HTT
SCHEMBL24145329 0.82 GAA (0.36) TDP1KMT2ALMNAGAASMN1; SMN2
SCHEMBL13071040 0.82 HTR2A (0.33) LMNAHTR2CHSD17B10HTR2A
SCHEMBL9188748 0.78 LMNA (0.41) TDP1KMT2ALMNAGAASMN1; SMN2
SCHEMBL2756772 0.78 HTR2A (0.33) LMNAHTR2CHSD17B10HTR2A
SCHEMBL24145291 0.78 LMNA (0.35) TDP1KMT2ALMNAGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1139107-A Method for recovering phenol and xanthene values from waste polycarbonate GEN ELECTRIC (US) 1997-01-01 CN claimed
EP-0738702-A1 Method for recovering phenol and xanthene values from waste polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-10-23 EP claimed
US-5567829-A Method for recovering phenol and xanthene values from waste polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-10-22 US claimed
US-5430199-A Method for recovering phenol and xanthene values from bisphenol A tars GENERAL ELECTRIC COMPANY (US) 1995-07-04 US claimed
US-11312668-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose ABBVIE INC. (US) 2022-04-26 US disclosed
US-20210047457-A1 COMPOUND, RESIN, COMPOSITION AND PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-02-18 US disclosed
US-20190237679-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-01 US disclosed
US-9741934-B2 Polymer compound and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-22 US disclosed
US-20170092864-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-30 US disclosed
US-9410016-B2 Aromatic polyacetals and articles comprising them DOW GLOBAL TECHNOLOGIES LLC (US) 2016-08-09 US disclosed
US-20150025278-A1 AROMATIC POLYACETALS AND ARTICLES COMPRISING THEM U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2015-01-22 US disclosed
WO-2005063730-A1 METHOD FOR THE PRODUCTION OF XANTHENE-4,5-DIOLES SUBSTITUTED IN POSITION 2.7 BASF AKTIENGESELLSCHAFT (DE) 2005-07-14 WO disclosed
WO-2002068434-A1 NOVEL DIPHOSPHINES AND A METHOD FOR THEIR PRODUCTION CELANESE CHEMICALS EUROPE GMBH (DE) 2002-09-06 WO disclosed
EP-0738723-B1 Method for making polyalkylated xanthenes GEN ELECTRIC (US) 2002-03-13 EP disclosed
CN-1139107-A Method for recovering phenol and xanthene values from waste polycarbonate GEN ELECTRIC (US) 1997-01-01 CN disclosed
EP-0738723-A2 Method for making polyalkylated xanthenes GENERAL ELECTRIC COMPANY (US) 1996-10-23 EP disclosed
EP-0738702-A1 Method for recovering phenol and xanthene values from waste polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-10-23 EP disclosed
US-5567829-A Method for recovering phenol and xanthene values from waste polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-10-22 US disclosed
US-5554770-A Method for making polyalkylated xanthenes GENERAL ELECTRIC COMPANY (US) 1996-09-10 US disclosed
US-5430199-A Method for recovering phenol and xanthene values from bisphenol A tars GENERAL ELECTRIC COMPANY (US) 1995-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170092864-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME CRY1, CCNA1, H1-0 MAPT 2698/4885THRB 1928/4885TDP1 3103/4885
US-20150025278-A1 AROMATIC POLYACETALS AND ARTICLES COMPRISING THEM AR, PARP1, PARG MAPT 1051/4885THRB 4271/4885TDP1 1672/4885
US-11312668-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose LIPA, ALG1, CEL MAPT 3070/4885THRB 4775/4885TDP1 614/4885
US-20190237679-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, SUN2 MAPT 1001/4885THRB 4430/4885TDP1 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.