Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | TPMT | P51580 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NCEH1 | Q6PIU2 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | RARA | P10276 | 2/20 | 0.51 |
| ▸ | RARB | P10826 | 2/20 | 0.51 |
| ▸ | RARG | P13631 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736295 | 0.88 | NCEH1 (0.53) | NCEH1LMNACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4674412 | 0.86 | NCEH1 (0.52) | CA12CA1CA2CA4CA6 | |
| SCHEMBL7469108 | 0.85 | CYP1A2 (0.65) | KDM4ENCEH1HTTLMNAMAPK1 | |
| SCHEMBL11806099 | 0.85 | NCEH1 (0.49) | CA12CA1CA2CA4CA6 | |
| SCHEMBL7772381 | 0.84 | MEN1 (0.51) | KDM4ENCEH1LMNARAB9ACYP19A1 | |
| SCHEMBL7741795 | 0.83 | NCEH1 (0.47) | CA12CA1CA2CA4CA6 | |
| SCHEMBL7741792 | 0.83 | NCEH1 (0.47) | CA12CA1CA2CA4CA6 | |
| SCHEMBL7572866 | 0.83 | TPMT (0.59) | CA12CA1CA2CA4CA6 | |
| SCHEMBL7776625 | 0.82 | ALDH1A1 (0.53) | NCEH1LMNACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9782904 | 0.82 | ALDH1A1 (0.53) | NCEH1LMNACYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977723-A1 | PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYARENECARBOXYLIC ACIDS | Finetech Ltd (IL) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998047853-A1 | PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYARENECARBOXYLIC ACIDS | FINETECH LTD. (IL) | 1998-10-29 | — | — | WO | disclosed |