SCHEMBL8165960

SCHEMBL8165960

OCCN1c2ccccc2Nc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.49
ALDH1A1 P00352 4/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
TP53 P04637 3/20 0.49
KDM4E B2RXH2 1/20 0.49
HSD17B10 Q99714 1/20 0.49
GAA P10253 2/20 0.46
HTR2A P28223 3/20 0.44
HTR1A P08908 2/20 0.44
ADRA2A P08913 2/20 0.44
DRD2 P14416 2/20 0.44
ADRA2B P18089 2/20 0.44
ADRA2C P18825 2/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
ADRA1A P35348 2/20 0.44
HRH1 P35367 2/20 0.44
DRD3 P35462 2/20 0.44
SLC6A3 Q01959 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8170132 0.88 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1NPC1RAB9ATP53
SCHEMBL5711025 0.82 HTR2A (0.47) SMN1; SMN2ALDH1A1NPC1RAB9ATP53
SCHEMBL29833637 0.82 HTR2A (0.47) SMN1; SMN2ALDH1A1NPC1RAB9ATP53
SCHEMBL7164942 0.78 GAA (0.46) SMN1; SMN2ALDH1A1NPC1RAB9ATP53
Bicarbonate SCHEMBL31429494 0.77 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1NPC1RAB9ATP53
SCHEMBL4571023 0.76 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1NPC1RAB9ATP53
SCHEMBL4571021 0.76 HTR2A (0.58) SMN1; SMN2ALDH1A1NPC1RAB9ATP53
SCHEMBL4571028 0.74 MEN1 (0.49) SMN1; SMN2ALDH1A1NPC1RAB9ATP53
SCHEMBL2287889 0.74 GAA (0.48) SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA
SCHEMBL12265301 0.73 CYP2D6 (0.66) SMN1; SMN2ALDH1A1NPC1RAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000028087-A1 A LIBRARY OF MODIFIED PRIMERS FOR NUCLEIC ACID SEQUENCING, AND METHOD OF USE THEREOF SEQUETECH CORPORATION (US) 2000-05-18 WO claimed
US-20250137035-A1 HYBRIDIZATION PROBES CONTAINING FLUORINATED CARBON CHAINS AND RELATED METHODS IDBYDNA INC. 2025-05-01 US disclosed
EP-4396370-A1 HYBRIDIZATION PROBES CONTAINING FLUORINATED CARBON CHAINS AND RELATED METHODS ILLUMINA, INC. (US) 2024-07-10 EP disclosed
CN-117940578-A Hybridization probes containing fluorinated carbon chains and related methods 因美纳有限公司 2024-04-26 CN disclosed
WO-2023034969-A1 HYBRIDIZATION PROBES CONTAINING FLUORINATED CARBON CHAINS AND RELATED METHODS IDBYDNA INC. (US) 2023-03-09 WO disclosed
WO-2000028087-A1 A LIBRARY OF MODIFIED PRIMERS FOR NUCLEIC ACID SEQUENCING, AND METHOD OF USE THEREOF SEQUETECH CORPORATION (US) 2000-05-18 WO disclosed