Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165960 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL5711013 | 0.84 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL30634565 | 0.84 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL5711036 | 0.84 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL909935 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL5710968 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL30634566 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL7164942 | 0.78 | GAA (0.46) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL4571021 | 0.77 | HTR2A (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL4571023 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000028087-A1 | A LIBRARY OF MODIFIED PRIMERS FOR NUCLEIC ACID SEQUENCING, AND METHOD OF USE THEREOF | SEQUETECH CORPORATION (US) | 2000-05-18 | — | — | WO | disclosed |