Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 9/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | HTR1A | P08908 | 7/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | DRD2 | P14416 | 6/20 | 0.63 |
| ▸ | HRH1 | P35367 | 6/20 | 0.63 |
| ▸ | HTR2A | P28223 | 5/20 | 0.63 |
| ▸ | HTR6 | P50406 | 5/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.63 |
| ▸ | DRD1 | P21728 | 5/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.63 |
| ▸ | DRD3 | P35462 | 5/20 | 0.63 |
| ▸ | MTOR | P42345 | 5/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Promazine SCHEMBL6855138 | 0.83 | CYP2D6 (0.83) | CYP2D6CYP1A2KMT2AHTR1ASLC6A4 | |
| SCHEMBL7164942 | 0.79 | GAA (0.46) | CYP2D6CYP1A2KMT2AMAPTDRD2 | |
| Dimetacrine SCHEMBL50120 | 0.79 | CYP2D6 (1.00) | CYP2D6CYP1A2KMT2AHTR1ASLC6A4 | |
| Dimetacrine SCHEMBL29578094 | 0.79 | CYP2D6 (1.00) | CYP2D6CYP1A2KMT2AHTR1ASLC6A4 | |
| Depramine SCHEMBL29489714 | 0.79 | HTR1A (0.73) | CYP2D6CYP1A2KMT2AHTR1ASLC6A4 | |
| Depramine SCHEMBL2108027 | 0.79 | HTR1A (0.73) | CYP2D6CYP1A2KMT2AHTR1ASLC6A4 | |
| SCHEMBL4571023 | 0.78 | SMN1; SMN2 (0.40) | CYP2D6CYP1A2KMT2AHTR1ASLC6A4 | |
| Imipramine SCHEMBL17004048 | 0.77 | SLC6A4 (1.00) | CYP2D6CYP1A2KMT2AHTR1ASLC6A4 | |
| Promazine SCHEMBL140489 | 0.77 | CYP2D6 (1.00) | CYP2D6CYP1A2KMT2AHTR1ASLC6A4 | |
| Promazine SCHEMBL9052694 | 0.77 | CYP2D6 (1.00) | CYP2D6CYP1A2KMT2AHTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110223221-A1 | STABILIZATION PROCESSES OF CATION RADICALS OF PHENOTHIAZINIC COMPOUNDS, COSMECEUTICAL FORMULATIONS AND METHODS FOR SKIN DISEASES AND DISTURBANCES PREVENTION | NANTES ISELI LOURENCO | 2011-09-15 | — | — | US | disclosed |
| US-20110223221-A1 | STABILIZATION PROCESSES OF CATION RADICALS OF PHENOTHIAZINIC COMPOUNDS, COSMECEUTICAL FORMULATIONS AND METHODS FOR SKIN DISEASES AND DISTURBANCES PREVENTION | NANTES ISELI LOURENCO | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110223221-A1 | STABILIZATION PROCESSES OF CATION RADICALS OF PHENOTHIAZINIC COMPOUNDS, COSMECEUTICAL FORMULATIONS AND METHODS FOR SKIN DISEASES AND DISTURBANCES PREVENTION | TYR, TXNRD2, NFE2L2 | CYP2D6 569/4885CYP1A2 1198/4885KMT2A 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.