Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.67 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653236 | 0.88 | ALOX5 (0.68) | ALOX5PIK3CDLMNA | |
| SCHEMBL7656075 | 0.82 | ALOX5 (0.69) | ALOX5PIK3CDALDH1A1LMNATSHR | |
| SCHEMBL7654887 | 0.82 | ALOX5 (0.68) | ALOX5PIK3CDALDH1A1LMNATSHR | |
| SCHEMBL3568549 | 0.81 | ALOX5 (0.62) | ALOX5PIK3CDHRH3 | |
| SCHEMBL7655164 | 0.81 | ALOX5 (0.67) | ALOX5F9 | |
| SCHEMBL8173632 | 0.81 | ALOX5 (0.67) | ALOX5ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL7651817 | 0.80 | ALOX5 (0.66) | ALOX5PIK3CDALDH1A1LMNATSHR | |
| SCHEMBL332442 | 0.80 | ALOX5 (1.00) | ALOX5PIK3CDALDH1A1 | |
| SCHEMBL29405839 | 0.80 | ALOX5 (1.00) | ALOX5PIK3CDALDH1A1 | |
| SCHEMBL332226 | 0.80 | ALOX5 (0.66) | ALOX5PIK3CDALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063928-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, CARDIOTONIC AGENTS | PFIZER INC (US) | 2000-05-16 | — | — | US | disclosed |