Phosphine

Phosphine

SCHEMBL8166357

Cc1ccccc1-c1[nH]nnc1C(=O)O.P

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 3/20 0.40
▸ GAA P10253 2/20 0.39
▸ MYC P01106 1/20 0.39
▸ KDM5A P29375 1/20 0.38
▸ KDM4C Q9H3R0 1/20 0.38
▸ KDM5B Q9UGL1 1/20 0.38
▸ MCL1 Q07820 1/20 0.38
▸ NR1H4 Q96RI1 1/20 0.37
▸ PIN1 Q13526 1/20 0.36
▸ NOTUM Q6P988 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ NPC1 O15118 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ CASP3 P42574 1/20 0.36
▸ SENP8 Q96LD8 1/20 0.36
▸ SENP7 Q9BQF6 1/20 0.36
▸ SENP6 Q9GZR1 1/20 0.36
▸ IKBKB O14920 1/20 0.35
▸ SLC9A1 P19634 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1290355 0.98 HPGD (0.41) HPGDGAAMYCKDM5AKDM4C
SCHEMBL7599243 0.83 GAA (0.38) HPGDGAAKDM5AKDM4CKDM5B
SCHEMBL20028652 0.76 KDM4E (0.46) HPGDGAAPIN1NPC1RAB9A
SCHEMBL29818805 0.76 KDM4E (0.41) HPGDGAANOTUMNPC1RAB9A
SCHEMBL30839322 0.74 GAA (0.41) HPGDGAANOTUMHTTNPC1
SCHEMBL23294571 0.73 HAO1 (0.41) HPGDGAAMYCKDM5AKDM4C
SCHEMBL28327759 0.73 GAA (0.46) HPGDGAANOTUMHTTNPC1
SCHEMBL6422752 0.73 CDC25B (0.32) GAASLC9A1ALDH1A1MEN1LMNA
SCHEMBL21312715 0.73 MCL1 (0.40) HPGDMCL1NR1H4PIN1
SCHEMBL21312600 0.73 PPARG (0.43) MCL1NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0759354-B1 LAMINATE OF VULCANIZABLE RUBBER COMPOSITION LAYERS, PROCESS FOR PRODUCING A VULCANIZED RUBBER LAMINATE, AND RUBBER LAMINATE NIPPON ZEON CO (JP) 2000-08-16 — — EP disclosed
US-5855976-A HOSE, DIAPHRAGM NIPPON ZEON CO., LTD. (JP) 1999-01-05 — — US disclosed
EP-0759354-A1 LAMINATE OF VULCANIZABLE RUBBER COMPOSITION LAYERS, PROCESS FOR PRODUCING RUBBER LAMINATE, AND RUBBER LAMINATE NIPPON ZEON CO., LTD. (JP) 1997-02-26 — — EP disclosed
Send feedback