Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422752 | 0.85 | CDC25B (0.32) | GAASLC9A1ALDH1A1USP2LMNA | |
| SCHEMBL1290355 | 0.84 | HPGD (0.41) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| Phosphine SCHEMBL8166357 | 0.83 | HPGD (0.40) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28327759 | 0.72 | GAA (0.46) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29818805 | 0.72 | KDM4E (0.41) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9173123 | 0.71 | GAA (0.39) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27599916 | 0.70 | GAA (0.44) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2918163 | 0.70 | PIK3CD (0.49) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28805494 | 0.70 | GAA (0.45) | GAANOTUMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30839322 | 0.70 | GAA (0.41) | GAANOTUMRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048986-B1 | Compositions for stripping photoresists in the manufacture of integrated circuits | ATOFINA (FR) | 2002-12-18 | — | — | EP | claimed |
| US-6291410-B1 | MIXTURE OF DIMETHYL SULPHOXIDE DMSO) OR N-METHYLPYRROLIDONE (NMP) AND 3-METHOXYPROPYLAMINE (MOPA). | ELF ATOCHEM S.A. (FR) | 2001-09-18 | — | — | US | claimed |
| US-9212340-B2 | Polymer-cleaning composition | ARKEMA FRANCE (FR) | 2015-12-15 | — | — | US | disclosed |
| US-20130310297-A1 | POLYMER-CLEANING COMPOSITION | ARKEMA FRANCE (FR) | 2013-11-21 | — | — | US | disclosed |
| CN-1130454-C | Composition for cleaning photoetching glue in integrated circuit production | ALF ATOCHEM S A (FR) | 2003-12-10 | — | — | CN | disclosed |
| CN-1130454-C | Composition for cleaning photoetching glue in integrated circuit production | ALF ATOCHEM S A (FR) | 2003-12-10 | — | — | CN | disclosed |
| US-6291410-B1 | MIXTURE OF DIMETHYL SULPHOXIDE DMSO) OR N-METHYLPYRROLIDONE (NMP) AND 3-METHOXYPROPYLAMINE (MOPA). | ELF ATOCHEM S.A. (FR) | 2001-09-18 | — | — | US | disclosed |
| US-6291410-B1 | MIXTURE OF DIMETHYL SULPHOXIDE DMSO) OR N-METHYLPYRROLIDONE (NMP) AND 3-METHOXYPROPYLAMINE (MOPA). | ELF ATOCHEM S.A. (FR) | 2001-09-18 | — | — | US | disclosed |
| CN-1280172-A | Composition for cleaning photoetching glue in integrated circuit production | ALF ATOCHEM S A (FR) | 2001-01-17 | — | — | CN | disclosed |
| CN-1280172-A | Composition for cleaning photoetching glue in integrated circuit production | ALF ATOCHEM S A (FR) | 2001-01-17 | — | — | CN | disclosed |