SCHEMBL8166371

SCHEMBL8166371

CCCCOC(C)c1ccc(C(=O)O)c(C(=O)O)c1C(C)OCCCC

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 3/20 0.39
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
PLK1 P53350 3/20 0.37
RARB P10826 4/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 2/20 0.36
RARA P10276 1/20 0.36
PTPN11 Q06124 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL729708 0.92 RARB (0.43) PLA2G4BTSHRTP53PLK1RARB
SCHEMBL17797928 0.89 TSHR (0.38) PLA2G4BTSHRTP53PLK1RARB
SCHEMBL3679170 0.88 PLK1 (0.38) PLA2G4BTSHRTP53PLK1RARB
SCHEMBL17798482 0.86 PLK1 (0.36) PLA2G4BTSHRTP53PLK1RARB
SCHEMBL17797855 0.86 ALDH1A1 (0.35) TSHRKDM4EMEN1RECQLKMT2A
SCHEMBL17797796 0.84 TSHR (0.45) PLA2G4BTSHRTP53RARBKDM4E
SCHEMBL17797829 0.83 ALDH1A1 (0.40) TSHRRARBRECQLALDH1A1RARA
SCHEMBL17797845 0.83 ALDH1A1 (0.44) TSHRKDM4EMEN1RECQLKMT2A
SCHEMBL9011052 0.82 SLC37A4 (0.45) PLA2G4BTSHRTP53PLK1KDM4E
SCHEMBL3677299 0.80 TP53 (0.35) PLA2G4BTSHRTP53PLK1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9587086-B2 Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties EASTMAN CHEMICAL COMPANY (US) 2017-03-07 US disclosed
US-9365951-B2 Negative polarity on the nanofiber line KIMBERLY-CLARK WORLDWIDE, INC. (US) 2016-06-14 US disclosed
US-20160159051-A1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES SOLUTIA INC. (US) 2016-06-09 US disclosed
US-20160160005-A1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES SOLUTION INC. (US) 2016-06-09 US disclosed
US-20150211149-A1 Negative Polarity on the Nanofiber Line KIMBERLY-CLARK WORLDWIDE, INC. (US) 2015-07-30 US disclosed
US-20150090658-A1 Fiber having a Nanohair Surface Topography KIMBERLY-CLARK WORLDWIDE, INC. (US) 2015-04-02 US disclosed
WO-2000063291-A1 USE OF POLYOXYMETHYLENE MOULDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2000-10-26 WO disclosed
EP-0827947-A1 Process for the preparation of esters of carboxylic acid and therefor useful catalysts Degussa Aktiengesellschaft (DE) 1998-03-11 EP disclosed
WO-1994020569-A1 SHOCK-RESISTANT THERMOPLASTIC MOLDING MATERIALS WITH HIGH IMPACT RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1994-09-15 WO disclosed
EP-0191845-B1 AN ADDITIVE COMPOSITION FOR INCREASING THE CONDUCTIVITY OF AN ORGANIC POLYMER, AN ACTIVE HYDROGEN-CONTAINING COMPOSITION CONTAINING THE ADDITIVE COMPOSITION, AND AN ORGANIC POLYMER COMPOSITION CONTAINING THE ADDITIVE COMPOSITION THE DOW CHEMICAL COMPANY (US) 1990-11-07 EP disclosed
US-4618630-A ESPECIALLY FOR POLYURETHANE FOAM PRODUCTION THE DOW CHEMICAL CO. (US) 1986-10-21 US disclosed
WO-1986001521-A1 AN ADDITIVE COMPOSITION FOR INCREASING THE CONDUCTIVITY OF AN ORGANIC POLYMER, AN ACTIVE HYDROGEN-CONTAINING COMPOSITION CONTAINING THE ADDITIVE COMPOSITION, AND AN ORGANIC POLYMER COMPOSITION CONTAINING THE ADDITIVE COMPOSITION THE DOW CHEMICAL COMPANY (US) 1986-03-13 WO disclosed