Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.35 |
| ▸ | TUBB | P07437 | 4/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164304 | 1.00 | MEN1 (0.37) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL27993330 | 0.84 | KDM4E (0.50) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL8161543 | 0.82 | ABCB11 (0.37) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL8161308 | 0.82 | ABCB11 (0.37) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL1507161 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1CA12CA9SMN1; SMN2 | |
| SCHEMBL3357240 | 0.80 | KDM4E (0.44) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL23089892 | 0.79 | KDM4E (0.62) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL29371595 | 0.79 | KDM4E (0.62) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL9643968 | 0.70 | ABCB11 (0.67) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL9656365 | 0.70 | ABCB11 (0.40) | MEN1KMT2AKDM4EALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008495-A2 | ANTIPROLIFERATIVE NAPHTHOQUINONES, DERIVATIVES, COMPOSITIONS, AND USES THEREOF | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2000-02-17 | — | — | WO | disclosed |