Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MYC | P01106 | 2/20 | 0.54 |
| ▸ | MAX | P61244 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.50 |
| ▸ | NAT1 | P18440 | 3/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 2/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172015 | 0.85 | MYC (0.61) | NPC1MYCMAXRAB9ANAT1 | |
| SCHEMBL18102998 | 0.84 | NAT1 (0.59) | CISD1NAT1ADAMTS5CA2EPHX1 | |
| SCHEMBL8171894 | 0.84 | NAT1 (0.59) | CISD1NAT1ADAMTS5CA2EPHX1 | |
| SCHEMBL8173323 | 0.84 | CSNK2A2 (0.64) | NPC1MYCMAXRAB9ANAT1 | |
| SCHEMBL8708384 | 0.77 | PIM1 (0.61) | NPC1MYCMAXRAB9ANAT1 | |
| SCHEMBL8167436 | 0.76 | PIM1 (0.75) | NPC1MYCMAXRAB9ACISD1 | |
| SCHEMBL8167434 | 0.76 | PIM1 (0.75) | NPC1MYCMAXRAB9ACISD1 | |
| SCHEMBL8307763 | 0.74 | NAT1 (0.61) | NPC1MYCMAXRAB9ACISD1 | |
| SCHEMBL8713697 | 0.74 | NAT1 (0.61) | NPC1MYCMAXRAB9ACISD1 | |
| SCHEMBL8708264 | 0.73 | PDE4B (0.70) | CISD1NAT1ADAMTS5CA2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |