Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 3/20 | 0.61 |
| ▸ | MAX | P61244 | 3/20 | 0.61 |
| ▸ | NAT1 | P18440 | 3/20 | 0.61 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 2/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.47 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8166533 | 0.85 | NPC1 (0.54) | MYCMAXNAT1CRHBPCRHR2 | |
| SCHEMBL18102998 | 0.84 | NAT1 (0.59) | NAT1PTP4A3ADAMTS5PIM1CA2 | |
| SCHEMBL8171894 | 0.84 | NAT1 (0.59) | NAT1PTP4A3ADAMTS5PIM1CA2 | |
| SCHEMBL8173323 | 0.81 | CSNK2A2 (0.64) | MYCMAXNAT1NPC1RAB9A | |
| SCHEMBL8310456 | 0.77 | PIM1 (0.61) | MYCMAXNAT1PTP4A3NPC1 | |
| SCHEMBL8708384 | 0.77 | PIM1 (0.61) | MYCMAXNAT1PTP4A3NPC1 | |
| SCHEMBL1249069 | 0.76 | NAT1 (1.00) | MYCMAXNAT1CRHBPCRHR2 | |
| SCHEMBL20816059 | 0.76 | NAT1 (1.00) | MYCMAXNAT1CRHBPCRHR2 | |
| SCHEMBL8307763 | 0.74 | NAT1 (0.61) | MYCMAXNAT1PTP4A3NPC1 | |
| SCHEMBL8713697 | 0.74 | NAT1 (0.61) | MYCMAXNAT1PTP4A3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |