Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | F9 | P00740 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178667 | 0.87 | F9 (0.41) | GPR119F9MEN1KMT2APCSK9 | |
| SCHEMBL8179364 | 0.84 | ALDH1A1 (0.38) | IDO1 | |
| SCHEMBL8525429 | 0.82 | NR1H4 (0.40) | NR1H4IDO1GPR119F9MEN1 | |
| SCHEMBL8524146 | 0.81 | DHODH (0.38) | NR1H4HSD11B1CTSSGPR119F9 | |
| SCHEMBL8173897 | 0.81 | KMT2A (0.38) | NR1H4KMT2A | |
| SCHEMBL12267819 | 0.78 | KDM4E (0.32) | — | |
| SCHEMBL8179859 | 0.74 | MAPK14 (0.33) | NR1H4 | |
| SCHEMBL8492423 | 0.73 | PDE2A (0.38) | GPR119F9MEN1KMT2APCSK9 | |
| SCHEMBL8524135 | 0.73 | SMN1; SMN2 (0.39) | GPR119F9MEN1KMT2A | |
| SCHEMBL8494675 | 0.72 | NR1H4 (0.38) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035916-A1 | HERBICIDAL 4-BENZOYLISOXAZOLES | AVENTIS CROPSCIENCE S.A. (FR) | 2000-06-22 | — | — | WO | disclosed |