Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | DBH | P09172 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502717 | 0.93 | ESR1 (0.35) | ESR1DBH | |
| SCHEMBL10336447 | 0.87 | ESR1 (0.33) | ESR1 | |
| SCHEMBL5587884 | 0.85 | LDHA (0.33) | ESR1KDM4EALDH1A1HPGDLDHA | |
| SCHEMBL5586788 | 0.85 | LDHA (0.33) | ESR1KDM4EALDH1A1HPGDLDHA | |
| SCHEMBL172098 | 0.83 | SLC6A2 (0.31) | KDM4EALDH1A1HPGD | |
| SCHEMBL16575391 | 0.80 | KDM4E (0.32) | KDM4EALDH1A1HPGD | |
| SCHEMBL9504320 | 0.80 | ESR1 (0.41) | ESR1KDM4EALDH1A1HPGD | |
| SCHEMBL10985455 | 0.79 | GCGR (0.38) | — | |
| SCHEMBL9505791 | 0.78 | ESR1 (0.40) | ESR1KDM4EALDH1A1HPGD | |
| SCHEMBL10158116 | 0.78 | ESR1 (0.36) | ESR1DBH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511558-A | Multilayer body | 帝人株式会社 | 2020-08-07 | — | — | CN | disclosed |
| US-6139322-A | A BLENDS COMPRISING AN INTERPENETRATING POLYMER NETWORK POLYMERIC MATRIX AND A SELF-LUBRICATING SWOLLEN CROSSLINKED PARTICLES; USE IN DENTAL PROSTHESIS SUCH AS ARTIFICIAL TEETH, INLAYS, ONLAYS, FACINGS, CROWNS, BRIDGES, ARTIFICIAL BONE | DENTSPLY RESEARCH & DEVELOPMENT CORP (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0427300-A1 | Interpenetrating polymer network compositions | DENTSPLY INTERNATIONAL, INC. (US) | 1991-05-15 | — | — | EP | disclosed |
| EP-0142747-A2 | Interpenetrating polymer network compositions employing rubber-modified polymers | DENTSPLY INTERNATIONAL, INC. (US) | 1985-05-29 | — | — | EP | disclosed |