Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.37 |
| ▸ | RELA | Q04206 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252326 | 0.88 | TNF (0.48) | TNFNOD1KDM4EP2RY6NFKB1 | |
| SCHEMBL6256243 | 0.84 | KDM4E (0.42) | KDM4ENFKB1RAB9ANFKB2RELA | |
| SCHEMBL6253068 | 0.82 | KDM4E (0.43) | KDM4ENFKB1RAB9ANFKB2RELA | |
| SCHEMBL6256696 | 0.82 | TNF (0.54) | TNFNOD1KDM4EP2RY6RAB9A | |
| SCHEMBL6254103 | 0.80 | KDM4E (0.49) | TNFNOD1KDM4EP2RY6NFKB1 | |
| SCHEMBL6256118 | 0.79 | KDM4E (0.43) | KDM4ENFKB1RAB9ANFKB2RELA | |
| SCHEMBL6255359 | 0.79 | KDM4E (0.47) | TNFNOD1KDM4EP2RY6NFKB1 | |
| SCHEMBL6256338 | 0.78 | KDM4E (0.42) | KDM4ENFKB1RAB9ANFKB2RELA | |
| SCHEMBL6254362 | 0.74 | SMN1; SMN2 (0.49) | KDM4ENFKB1RAB9ANFKB2RELA | |
| SCHEMBL6254376 | 0.74 | SMN1; SMN2 (0.43) | KDM4ENFKB1RAB9ANFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |