Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 14/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29302774 | 0.75 | MAOB (0.47) | MAOAMAOBMAPTKDM4EPOLB | |
| SCHEMBL7008235 | 0.66 | MAOA (0.37) | MAOAMAOBMAPTKDM4EPOLB | |
| SCHEMBL7401281 | 0.65 | SMN1; SMN2 (0.46) | MAOAMAOBMAPTKDM4EPOLB | |
| SCHEMBL6414798 | 0.61 | MAOA (0.42) | MAOAMAOBMAPTKDM4EPOLB | |
| SCHEMBL1654265 | 0.57 | MAPT (0.48) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL160885 | 0.57 | — | — | |
| SCHEMBL598525 | 0.57 | TSHR (0.56) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL598863 | 0.57 | MAPT (0.46) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL20972837 | 0.56 | — | — | |
| SCHEMBL3938209 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048640-A1 | APOPTOSIS INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |