Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 13/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401281 | 0.67 | SMN1; SMN2 (0.46) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL8167208 | 0.66 | MAOA (0.36) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL160885 | 0.64 | — | — | |
| SCHEMBL6414798 | 0.63 | MAOA (0.42) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL22492035 | 0.61 | SMN1; SMN2 (0.46) | KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL30714392 | 0.59 | ALDH1A1 (0.35) | MAOAMAOBPOLBMAPTSMN1; SMN2 | |
| SCHEMBL10192881 | 0.58 | MEN1 (0.40) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL20972837 | 0.58 | — | — | |
| SCHEMBL3938209 | 0.58 | — | — | |
| SCHEMBL1176138 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324993-A2 | SUBSTITUTED 1,4-THIAZEPINE AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2001079187-A2 | SUBSTITUTED 1,4-THIAZEPINE AND ANALOGS AND THEIR USE AS ACTIVATORS OF CASPASES | CYTOVIA, INC. (US) | 2001-10-25 | — | — | WO | disclosed |