Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 3/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798650 | 0.84 | MAPK8 (0.62) | MAPK9MAPK8MAPK10ARCDK2 | |
| SCHEMBL1798645 | 0.84 | MAPK8 (0.62) | MAPK9MAPK8MAPK10ARCDK2 | |
| SCHEMBL1799003 | 0.83 | MAPK9 (0.40) | MAPK9MAPK8MAPK10SMN1; SMN2RAB9A | |
| SCHEMBL1799160 | 0.81 | HTR2C (0.38) | MAPK9MAPK8MAPK10NTRK1CDK5 | |
| SCHEMBL1796697 | 0.81 | IL2 (0.44) | MAPK9MAPK8MAPK10SMN1; SMN2CDK2 | |
| SCHEMBL1801749 | 0.80 | IL2 (0.39) | MAPK9MAPK8MAPK10CDK2CCNT1 | |
| SCHEMBL8168358 | 0.79 | MAPK8 (0.41) | MAPK9MAPK8MAPK10KDRROCK1 | |
| SCHEMBL1796713 | 0.79 | CAMKK2 (0.43) | MAPK9MAPK8MAPK10SMN1; SMN2KMT2A | |
| SCHEMBL1797816 | 0.78 | MEN1 (0.39) | MAPK9MAPK8MAPK10CDK2MAPK1 | |
| SCHEMBL15500796 | 0.78 | AXL (0.55) | SMN1; SMN2ARTP53HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095943-A1 | THE USE OF 7-AZAINDOLES IN THE INHIBITION OF C-JUN N-TERMINAL KINASE | EISAI R&D MANAGEMENT CO. LTD. (JP) | 2008-08-14 | — | — | WO | disclosed |