Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547425 | 0.82 | ALDH1A1 (0.42) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL10834300 | 0.82 | LMNA (0.52) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL2757911 | 0.82 | CYP3A4 (0.42) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL3274456 | 0.82 | ALDH1A1 (0.42) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL15289609 | 0.80 | — | — | |
| SCHEMBL11548108 | 0.80 | CYP3A4 (0.41) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11197857 | 0.80 | CYP3A4 (0.41) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL31492363 | 0.80 | CYP3A4 (0.41) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL5322857 | 0.79 | ALDH1A1 (0.43) | CYP3A4ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL19812427 | 0.79 | ALDH1A1 (0.43) | CYP3A4ALDH1A1TDP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106129-A2 | POLYMERIC MICELLES FOR COMBINATION DRUG DELIVERY | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-09-04 | — | — | WO | disclosed |