Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 17/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167391 | 1.00 | GLS (0.38) | GLSKMT2AALDH1A1PKMHTT | |
| SCHEMBL8218990 | 0.88 | GLS (0.39) | GLSKMT2A | |
| SCHEMBL8218077 | 0.78 | GLS (0.33) | GLSKMT2A | |
| SCHEMBL8167396 | 0.76 | GLS (0.38) | GLS | |
| SCHEMBL7457468 | 0.69 | HTT (0.51) | GLSKMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL8215964 | 0.68 | GLS (0.33) | GLS | |
| SCHEMBL7368805 | 0.67 | MEN1 (0.37) | GLSKMT2A | |
| SCHEMBL27853854 | 0.59 | KCNN4 (0.46) | KMT2AALDH1A1PKMHTT | |
| SCHEMBL15042315 | 0.57 | GLS (1.00) | GLS | |
| SCHEMBL14223636 | 0.56 | KCNN4 (0.48) | ALDH1A1PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | disclosed |