Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 19/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218081 | 0.79 | GLS (0.34) | GLS | |
| SCHEMBL8167391 | 0.76 | GLS (0.38) | GLS | |
| SCHEMBL8167394 | 0.76 | GLS (0.38) | GLS | |
| SCHEMBL7457468 | 0.70 | HTT (0.51) | GLS | |
| SCHEMBL7368805 | 0.67 | MEN1 (0.37) | GLS | |
| SCHEMBL8218990 | 0.63 | GLS (0.39) | GLS | |
| SCHEMBL5281607 | 0.61 | KMT2A (0.47) | — | |
| SCHEMBL6097619 | 0.57 | CA12 (0.51) | — | |
| SCHEMBL26047552 | 0.56 | ATM (0.50) | — | |
| SCHEMBL10419532 | 0.56 | PDE4A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | disclosed |