Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7177911 | 0.91 | PTGS2 (0.47) | PTGS2DNMT1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL28743345 | 0.88 | PTGS2 (0.43) | PTGS2DNMT1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL6287678 | 0.88 | PTGS2 (0.54) | PTGS2CYP11B1CYP11B2ALDH1A1GPR84 | |
| SCHEMBL19590927 | 0.76 | PTGS2 (0.56) | PTGS2DNMT1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL7180542 | 0.75 | PTGS2 (0.67) | PTGS2CYP11B1CYP11B2GPR84IP6K1 | |
| SCHEMBL29672905 | 0.75 | PTGS2 (0.67) | PTGS2CYP11B1CYP11B2GPR84IP6K1 | |
| SCHEMBL7181762 | 0.73 | PTGS2 (0.57) | PTGS2CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL29787010 | 0.73 | DNMT1 (0.59) | DNMT1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL196007 | 0.73 | DNMT1 (0.59) | DNMT1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL29410608 | 0.73 | DNMT1 (0.59) | DNMT1ALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1059300-A1 | Indenyl compounds for the polymerisation of olefins | DSM N.V. (NL) | 2000-12-13 | — | — | EP | disclosed |