Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178590 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2PLK1PLAULPL | |
| SCHEMBL1808750 | 0.83 | PLK1 (0.47) | ALDH1A1PLK1LPLLIPGTDP1 | |
| SCHEMBL1808751 | 0.83 | PLK1 (0.47) | ALDH1A1PLK1LPLLIPGTDP1 | |
| SCHEMBL11814265 | 0.81 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2L3MBTL1GAATSHR | |
| SCHEMBL505965 | 0.80 | CA1 (0.48) | SMN1; SMN2 | |
| SCHEMBL505964 | 0.80 | CA1 (0.48) | SMN1; SMN2 | |
| SCHEMBL2298579 | 0.80 | PRSS1 (0.45) | SMN1; SMN2HPGDTSHRNPC1RAB9A | |
| SCHEMBL2298580 | 0.80 | PRSS1 (0.45) | SMN1; SMN2HPGDTSHRNPC1RAB9A | |
| SCHEMBL18770623 | 0.79 | THRA (0.54) | ALDH1A1LPLLIPGLMNAMAPT | |
| SCHEMBL18770624 | 0.79 | THRA (0.54) | ALDH1A1LPLLIPGLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |