Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Triethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentaethylene Glycol SCHEMBL1627452 | 1.00 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1THRB | |
| Phosphoric Acid SCHEMBL899139 | 1.00 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL1573538 | 1.00 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL236335 | 1.00 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1THRB | |
| Hexaethylene Glycol SCHEMBL875412 | 1.00 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL874011 | 1.00 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL854457 | 1.00 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL125344 | 0.97 | TSHR (0.67) | MEN1KMT2ATSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL28090651 | 0.97 | TSHR (0.67) | MEN1KMT2ATSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL8621256 | 0.97 | TSHR (0.67) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590365-B1 | A method for producing polyamide with reduced flammability | BASF CORP (US) | 1998-05-27 | — | — | EP | claimed |
| EP-0589284-B1 | Thermoplastic polyamide with reduced flammability | BASF CORP (US) | 1996-11-27 | — | — | EP | claimed |
| US-5565545-A | USING CATALYST WITH CONTROLLED CONCENTRATION OG ANTIMONY, GERMANIUM AND PHOSPHORUS | ZIMMER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | claimed |
| US-5382474-A | Condensation polymerization, tris/alkylene glycol phosphate | BASF CORPORATION (US) | 1995-01-17 | — | — | US | claimed |
| US-5369160-A | Organic phosphate | BASF CORPORATION (US) | 1994-11-29 | — | — | US | claimed |
| US-5322883-A | Adding a polyalkylene glycol phosphate ester to condensation mixture | BASF CORPORATION (US) | 1994-06-21 | — | — | US | claimed |
| EP-0590365-A1 | A method for producing polyamide with reduced flammability | BASF CORPORATION (US) | 1994-04-06 | — | — | EP | claimed |
| EP-0589197-A1 | Thermoplastic polyester with reduced flammability | BASF CORPORATION (US) | 1994-03-30 | — | — | EP | claimed |
| EP-0589284-A1 | Thermoplastic polyamide with reduced flammability | BASF CORPORATION (US) | 1994-03-30 | — | — | EP | claimed |
| US-5238982-A | Melt mixing polyamide with phosphate ester, melt spinning | BASF CORPORATION (US) | 1993-08-24 | — | — | US | claimed |
| EP-0102115-B1 | POLYESTER-ESTER URETHANE | AKZO N.V. (NL) | 1987-06-10 | — | — | EP | claimed |
| US-4483970-A | BLOCK POLYMERS, MOLDING MATERIALS | AKZO N.V. (NL) | 1984-11-20 | — | — | US | claimed |
| EP-0102115-A1 | Polyester-ester urethane | AKZO N.V. (NL) | 1984-03-07 | — | — | EP | claimed |
| JP-6192569-A | — | — | None | — | — | JP | disclosed |
| WO-2025022961-A1 | METHOD FOR PRODUCING THERMOPLASTIC RESIN FILM, THERMOPLASTIC RESIN FILM, DRY FILM RESIST, AND RELEASE FILM | 富士フイルム株式会社 | 2025-01-30 | — | — | WO | disclosed |
| WO-2025018361-A1 | RESIN COMPOSITION AND MOLDED ARTICLE | 三菱ケミカル株式会社 | 2025-01-23 | — | — | WO | disclosed |
| EP-0159053-A1 | Polyester-ester urethane | AKZO N.V. (NL) | 1985-10-23 | — | — | EP | disclosed |
| US-4483970-A | BLOCK POLYMERS, MOLDING MATERIALS | AKZO N.V. (NL) | 1984-11-20 | — | — | US | disclosed |
| EP-0102115-A1 | Polyester-ester urethane | AKZO N.V. (NL) | 1984-03-07 | — | — | EP | disclosed |
| EP-0013461-B1 | PROCESS FOR THE PREPARATION OF A SEGMENTED THERMOPLASTIC ELASTOMER | AKZO N.V. (NL) | 1983-04-06 | — | — | EP | disclosed |