Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.60 |
| ▸ | HMGCR | P04035 | 15/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171503 | 0.90 | FDPS (0.61) | FDPSHMGCRPOLBHPGDTBXAS1 | |
| SCHEMBL8166214 | 0.85 | FDPS (0.66) | FDPSPOLBHPGDTBXAS1 | |
| SCHEMBL8167482 | 0.83 | FDPS (0.71) | FDPSPOLBHPGDTBXAS1 | |
| SCHEMBL6060892 | 0.82 | FDPS (0.60) | FDPSHMGCRPOLB | |
| SCHEMBL19939426 | 0.81 | HMGCR (0.55) | HMGCR | |
| SCHEMBL2459769 | 0.76 | FDPS (1.00) | FDPSTBXAS1 | |
| SCHEMBL31061112 | 0.76 | FDPS (1.00) | FDPSTBXAS1 | |
| SCHEMBL5662316 | 0.75 | FDPS (0.43) | FDPSHMGCRHPGD | |
| SCHEMBL15163928 | 0.75 | HMGCR (0.52) | HMGCR | |
| SCHEMBL24334938 | 0.75 | FDPS (0.53) | FDPSTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563107-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | disclosed |
| US-5393748-A | Treating bone disorders, Paget* s disease, calcium metabolism disorders | LEIRAS OY (FI) | 1995-02-28 | — | — | US | disclosed |