Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.71 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8166214 | 0.94 | FDPS (0.66) | FDPSBTN3A1PDE3APOLBHPGD | |
| SCHEMBL8171503 | 0.91 | FDPS (0.61) | FDPSBTN3A1PDE3APOLBHPGD | |
| SCHEMBL8167459 | 0.86 | FDPS (0.75) | FDPSBTN3A1PDE3ATBXAS1PKM | |
| Hydrochloric Acid SCHEMBL9174019 | 0.85 | FDPS (0.73) | FDPSBTN3A1PDE3ATBXAS1PKM | |
| SCHEMBL2459769 | 0.84 | FDPS (1.00) | FDPSBTN3A1PDE3ATBXAS1PKM | |
| SCHEMBL31061112 | 0.84 | FDPS (1.00) | FDPSBTN3A1PDE3ATBXAS1PKM | |
| SCHEMBL8167994 | 0.83 | FDPS (0.60) | FDPSPOLBHPGDTBXAS1 | |
| SCHEMBL9621950 | 0.83 | LAP3 (0.50) | FDPSPOLBKMT2AKDM4E | |
| SCHEMBL10001487 | 0.81 | FDPS (0.82) | FDPSBTN3A1PDE3ATBXAS1PKM | |
| Hydrochloric Acid SCHEMBL9169735 | 0.78 | FDPS (0.66) | FDPSBTN3A1PDE3ATBXAS1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563107-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | disclosed |
| US-5393748-A | Treating bone disorders, Paget* s disease, calcium metabolism disorders | LEIRAS OY (FI) | 1995-02-28 | — | — | US | disclosed |
| EP-0563107-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011269-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1992-07-09 | — | — | WO | disclosed |