Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATIC | P31939 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014873 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EGAACYP2D6AURKA | |
| SCHEMBL6757866 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EGAACYP2D6AURKA | |
| SCHEMBL28388789 | 0.80 | NR4A1 (0.40) | ALDH1A1KDM4EGAAATICCYP2D6 | |
| SCHEMBL28888192 | 0.77 | CASP6 (0.39) | ALDH1A1KDM4EGAACYP2D6MAPK1 | |
| SCHEMBL29627281 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAACYP2D6AURKA | |
| SCHEMBL5424908 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAACYP2D6AURKA | |
| SCHEMBL31738427 | 0.75 | KDM4E (0.39) | ALDH1A1KDM4EGAACYP2D6AURKA | |
| SCHEMBL253499 | 0.75 | KDM4E (0.39) | ALDH1A1KDM4EGAACYP2D6AURKA | |
| SCHEMBL11552259 | 0.73 | TTR (0.42) | ALDH1A1KDM4EGAATTRAURKA | |
| SCHEMBL8882563 | 0.73 | KDM4E (0.50) | ALDH1A1KDM4EGAACYP2D6AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093834-A | Preparation of perylene-3,4-dicarboxylic acid anhydrides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-07-25 | — | — | US | disclosed |
| US-5900490-A | Preparation of perylene-3, 4-Dicarboxylic acid anhydrides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-05-04 | — | — | US | disclosed |