Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | SHBG | P04278 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31511913 | 1.00 | SMN1; SMN2 (0.70) | SMN1; SMN2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL1039742 | 0.91 | SMN1; SMN2 (0.70) | SMN1; SMN2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL1245832 | 0.89 | MEN1 (0.70) | SMN1; SMN2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL29535974 | 0.89 | MEN1 (0.70) | SMN1; SMN2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL2292369 | 0.86 | CYP19A1 (0.71) | SMN1; SMN2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL30129997 | 0.86 | CYP19A1 (0.71) | SMN1; SMN2HPGDMEN1KMT2ARAB9A | |
| Ononetin SCHEMBL2948430 | 0.82 | NPC1 (1.00) | SMN1; SMN2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL3965268 | 0.82 | GAA (0.83) | HPGDMEN1KMT2ARAB9AALDH1A1 | |
| Ononetin SCHEMBL30203900 | 0.82 | NPC1 (1.00) | SMN1; SMN2HPGDMEN1KMT2ARAB9A | |
| SCHEMBL3068438 | 0.82 | ESR1 (0.77) | SMN1; SMN2HPGDMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278394-A1 | POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF | FIRMENICH INCORPORATED (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2009129260-A2 | CALYCOSIN AND ANALOGS THEREOF FOR THE TREATMENT OF ESTROGEN RECEPTOR BETA-MEDIATED DISEASES | BIONOVO, INC. (US) | 2009-10-22 | — | — | WO | disclosed |
| US-20090258942-A1 | CALYCOSIN AND ANALOGS THEREOF FOR THE TREATMENT OF ESTROGEN RECEPTOR BETA-MEDIATED DISEASES | BIONOVO, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| US-20090258942-A1 | CALYCOSIN AND ANALOGS THEREOF FOR THE TREATMENT OF ESTROGEN RECEPTOR BETA-MEDIATED DISEASES | BIONOVO, INC. (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258942-A1 | CALYCOSIN AND ANALOGS THEREOF FOR THE TREATMENT OF ESTROGEN RECEPTOR BETA-MEDIATED DISEASES | GPER1, ESRRG, CALR | SMN1; SMN2 2783/4885HPGD 2287/4885MEN1 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.