Sugi Predict

Sugi Predict / Compounds / SCHEMBL2292369

SCHEMBL2292369

SCHEMBL2292369

COc1ccc(CCC(=O)c2ccc(O)cc2O)cc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 1/20 0.71
▸ MEN1 O00255 4/20 0.67
▸ KMT2A Q03164 4/20 0.67
▸ CYP3A4 P08684 3/20 0.59
▸ ALDH1A1 P00352 2/20 0.59
▸ HPGD P15428 2/20 0.59
▸ NPC1 O15118 1/20 0.59
▸ RAB9A P51151 1/20 0.59
▸ ATM Q13315 1/20 0.59
▸ SMN1; SMN2 Q16637 1/20 0.59
▸ TTR P02766 1/20 0.53
▸ CYP1A2 P05177 1/20 0.52
▸ TSHR P16473 1/20 0.52
▸ NFKB1 P19838 1/20 0.52
▸ LMNA P02545 1/20 0.51
▸ APEX1 P27695 1/20 0.51
▸ GAA P10253 1/20 0.51
▸ ALOX5 P09917 1/20 0.51
▸ OR51E2 Q9H255 1/20 0.51
▸ SLC5A1 P13866 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30129997 1.00 CYP19A1 (0.71) CYP19A1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL9730692 0.92 MEN1 (0.67) CYP19A1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL31511909 0.89 MEN1 (0.67) CYP19A1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL1840837 0.89 MEN1 (0.67) CYP19A1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL12379820 0.88 CYP19A1 (0.62) CYP19A1MEN1KMT2ACYP3A4NPC1
SCHEMBL31511913 0.86 SMN1; SMN2 (0.70) CYP19A1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL8168221 0.86 SMN1; SMN2 (0.70) CYP19A1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL10328456 0.85 CYP19A1 (0.65) CYP19A1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL4656453 0.85 MEN1 (0.76) CYP19A1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL31511903 0.85 MEN1 (0.76) CYP19A1MEN1KMT2ACYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200397026-A1 ANTIMICROBIALLY ACTIVE MIXTURES SYMRISE AG (DE) 2020-12-24 — — US claimed
EP-3709820-A1 ANTIMICROBIALLY ACTIVE MIXTURES Symrise AG (DE) 2020-09-23 — — EP claimed
CN-111328261-A Mixture with antimicrobial action 西姆莱斯有限公司 2020-06-23 — — CN claimed
CN-105636453-B Substance mixture 西姆莱斯股份公司 2019-12-24 — — CN claimed
EP-2868209-B1 Compound mixtures SYMRISE AG (DE) 2019-04-03 — — EP claimed
EP-2954785-B1 New composition for improvement of sweet taste comprising rubusoside or alpha-glycolsylrubusoside SYMRISE AG (DE) 2018-06-06 — — EP claimed
EP-2883459-B1 Compositions for oral consumption SYMRISE AG (DE) 2018-04-04 — — EP claimed
US-20170190727-A1 NOVEL MATERIAL MIXTURE CONTAINING RUBUSOSIDE OR ALPHA GLYCOSYLRUBUSOSIDE, FOR ENHANCING SWEET TASTE SYMRISE AG (DE) 2017-07-06 — — US claimed
US-20160295892-A1 MIXTURES OF MATTER SYMRISE AG (DE) 2016-10-13 — — US claimed
EP-2954785-A1 New composition for improvement of sweet taste comprising rubusoside or alpha-glycolsylrubusoside Symrise AG (DE) 2015-12-16 — — EP claimed
EP-2868209-A1 Compound mixtures Symrise AG (DE) 2015-05-06 — — EP claimed
EP-2353403-B1 Use of 1-(2,4-dihydroxy-phenyl)-3-(3-hydroxy-4-methoxy-phenyl)-propan-1-on SYMRISE AG (DE) 2012-07-11 — — EP claimed
EP-2353403-A1 Use of 1-(2,4-dihydroxy-phenyl)-3-(3-hydroxy-4-methoxy-phenyl)-propan-1-on Symrise AG (DE) 2011-08-10 — — EP claimed
US-20110189108-A1 USE OF 1-(2,4-DIHYDROXY-PHENYL)-3-(3-HYDROXY-4-METHOXY-PHENYL)-PROPAN-1-ONE SYMRISE AG (DE) 2011-08-04 — — US claimed
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 — — US disclosed
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES OSMO LABS PBC (US) 2026-01-29 — — US disclosed
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS, PBC 2025-10-09 — — US disclosed
US-20110189108-A1 USE OF 1-(2,4-DIHYDROXY-PHENYL)-3-(3-HYDROXY-4-METHOXY-PHENYL)-PROPAN-1-ONE SYMRISE AG (DE) 2011-08-04 — — US disclosed
US-20110189108-A1 USE OF 1-(2,4-DIHYDROXY-PHENYL)-3-(3-HYDROXY-4-METHOXY-PHENYL)-PROPAN-1-ONE SYMRISE AG (DE) 2011-08-04 — — US disclosed
US-3956375-A 1,3-Diphenyl-propanone-1-derivatives and the salts thereof CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT (HU) 1976-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160295892-A1 MIXTURES OF MATTER HES1, SORD, PNN CYP19A1 1351/4885MEN1 366/4885KMT2A 1790/4885
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CYP8B1, CYP1B1, BBOX1 CYP19A1 92/4885MEN1 1752/4885KMT2A 2702/4885
US-20170190727-A1 NOVEL MATERIAL MIXTURE CONTAINING RUBUSOSIDE OR ALPHA GLYCOSYLRUBUSOSIDE, FOR ENHANCING SWEET TASTE TAS2R40, TAS2R31, TAS2R38 CYP19A1 3767/4885MEN1 2958/4885KMT2A 2941/4885
US-20110189108-A1 USE OF 1-(2,4-DIHYDROXY-PHENYL)-3-(3-HYDROXY-4-METHOXY-PHENYL)-PROPAN-1-ONE HES1, TAS2R20, TAS2R50 CYP19A1 4353/4885MEN1 1213/4885KMT2A 3183/4885
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES TAS2R42, TAS2R4, TAS2R41 CYP19A1 720/4885MEN1 2841/4885KMT2A 733/4885
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 CYP19A1 203/4885MEN1 3787/4885KMT2A 3953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.