Butachlor

Butachlor

SCHEMBL8169078

CC(C)N(C(=O)CCl)c1ccccc1.CCCCOCN(C(=O)CCl)c1c(CC)cccc1CC

nearest known ligand 0.76

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.76
KMT2A Q03164 3/20 0.76
MEN1 O00255 2/20 0.76
ALDH1A1 P00352 9/20 0.55
TP53 P04637 6/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
LMNA P02545 1/20 0.55
NR1I2 O75469 1/20 0.52
CYP3A4 P08684 1/20 0.52
NPC1 O15118 5/20 0.45
RAB9A P51151 5/20 0.45
PAX8 Q06710 4/20 0.45
JAK2 O60674 2/20 0.45
GPX4 P36969 1/20 0.39
HTT P42858 3/20 0.36
GLA P06280 1/20 0.36
MAPT P10636 1/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butachlor SCHEMBL4891145 0.87 TDP1 (1.00) TDP1KMT2AMEN1ALDH1A1TP53
Butachlor SCHEMBL65784 0.87 TDP1 (1.00) TDP1KMT2AMEN1ALDH1A1TP53
Butachlor SCHEMBL17110610 0.86 TDP1 (0.88) TDP1KMT2AMEN1ALDH1A1TP53
Butachlor SCHEMBL11052762 0.82 TDP1 (0.90) TDP1KMT2AMEN1ALDH1A1TP53
Butachlor SCHEMBL8167808 0.80 KMT2A (0.77) TDP1KMT2AMEN1ALDH1A1TP53
SCHEMBL9614001 0.80 TDP1 (0.85) TDP1KMT2AMEN1ALDH1A1TP53
Butachlor SCHEMBL23242441 0.80 TDP1 (0.84) TDP1KMT2AMEN1ALDH1A1TP53
Butachlor SCHEMBL8846427 0.80 TDP1 (0.84) TDP1KMT2AMEN1ALDH1A1TP53
Propachlor SCHEMBL4294229 0.80 ALDH1A1 (0.60) TDP1KMT2AMEN1ALDH1A1TP53
Butachlor SCHEMBL15917627 0.79 TDP1 (0.74) TDP1KMT2AMEN1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0994650-A2 MICROPARTICLES CONTAINING AGRICULTURAL ACTIVE INGREDIENTS MONSANTO COMPANY (US) 2000-04-26 EP disclosed
WO-1999000013-A2 MICROPARTICLES CONTAINING AGRICULTURAL ACTIVE INGREDIENTS MONSANTO COMPANY (US) 1999-01-07 WO disclosed