Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 11/20 | 0.49 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.48 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | S100B | P04271 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | AOC1 | P19801 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163067 | 0.82 | PRSS1 (0.54) | PRSS1F2ST14PLGPLAU | |
| SCHEMBL8176603 | 0.79 | NQO2 (0.48) | PRSS1PRMT1F2PLGPLAU | |
| SCHEMBL8007736 | 0.77 | CYP19A1 (0.48) | CYP2D6 | |
| SCHEMBL8170510 | 0.77 | NQO2 (0.44) | PRSS1PRMT1F2PLGPLAU | |
| SCHEMBL9650651 | 0.76 | PRSS1 (0.81) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL9783835 | 0.76 | NR5A1 (0.50) | CYP2D6 | |
| SCHEMBL11016291 | 0.75 | LTA4H (0.53) | CYP2D6 | |
| Hydrochloric Acid SCHEMBL11182186 | 0.75 | PRSS1 (0.82) | PRSS1TMPRSS2PRMT1F2ST14 | |
| Hydrochloric Acid SCHEMBL7796572 | 0.75 | PRSS1 (0.75) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL8169720 | 0.74 | C1S (0.44) | PRSS1PRMT1F2ST14PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114328-A | ANTICOAGULANTS; BLOOD DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-09-05 | — | — | US | disclosed |
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |