Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173592 | 0.94 | ALDH1A1 (0.62) | LMNAALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL8161721 | 0.92 | LMNA (0.49) | LMNAALDH1A1KDM4EL3MBTL1ATM | |
| SCHEMBL8169322 | 0.90 | LMNA (0.65) | LMNAALDH1A1KDM4EATMSMN1; SMN2 | |
| SCHEMBL8168307 | 0.90 | KDM4E (0.50) | LMNAALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL8168304 | 0.90 | KDM4E (0.50) | LMNAALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL7604154 | 0.89 | LMNA (0.66) | LMNAALDH1A1 | |
| SCHEMBL8173849 | 0.89 | ALDH1A1 (0.49) | LMNAALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL8173853 | 0.89 | ALDH1A1 (0.49) | LMNAALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL8161909 | 0.89 | LMNA (0.61) | LMNAALDH1A1KDM4EMAPTMAPK1 | |
| Oxalic Acid SCHEMBL8161910 | 0.89 | LMNA (0.65) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060468-A | ANTIINFLAMMATORY AGENTS | NOVO NORDISK A/S (DK) | 2000-05-09 | — | — | US | disclosed |
| EP-0934314-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015550-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |