Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830664 | 0.82 | PRCP (0.39) | TSHRTNKS2MAPTTDP1LMNA | |
| SCHEMBL28385224 | 0.80 | KIF11 (0.37) | MAPTTDP1L3MBTL1KDM1ANPC1 | |
| SCHEMBL1028466 | 0.79 | HTR2A (0.39) | LMNAHTR6HTR2AALDH1A1SLC6A2 | |
| SCHEMBL17835299 | 0.79 | ALDH1A1 (0.36) | TSHRTDP1L3MBTL1LMNAHDAC2 | |
| SCHEMBL30355050 | 0.79 | ALDH1A1 (0.36) | TSHRTDP1L3MBTL1LMNAHDAC2 | |
| Ammonia Solution, Strong SCHEMBL21245914 | 0.77 | HTR2A (0.38) | LMNAHTR6HTR2AALDH1A1SLC6A2 | |
| SCHEMBL9145143 | 0.77 | HTR2A (0.38) | LMNAHTR6HTR2AALDH1A1SLC6A2 | |
| Methane SCHEMBL28813011 | 0.77 | HTR2A (0.38) | LMNAHTR6HTR2AALDH1A1SLC6A2 | |
| SCHEMBL9145856 | 0.77 | HTR2A (0.38) | LMNAHTR6HTR2AALDH1A1SLC6A2 | |
| SCHEMBL9145850 | 0.77 | HTR2A (0.38) | LMNAHTR6HTR2AALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102964371-B | A kind of preparation method of silicon bridge vicinal resistance type cyclopentadiene compounds | SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2015-08-12 | — | — | CN | claimed |
| CN-102964371-A | Preparation method of silicon-bridged sterically-hindered cyclopentadiene compound | SHANGHAI RES INST CHEMICAL IND | 2013-03-13 | — | — | CN | claimed |
| EP-2935297-B1 | BRIDGED METALLOCENE COMPOUNDS, CATALYST SYSTEMS AND PROCESSES FOR POLYMERIZATION THEREWITH | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-03-20 | — | — | EP | disclosed |
| US-9266977-B2 | Bridged metallocene compounds, catalyst systems and processes for polymerization therewith | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-02-23 | — | — | US | disclosed |
| EP-2935297-A1 | BRIDGED METALLOCENE COMPOUNDS, CATALYST SYSTEMS AND PROCESSES FOR POLYMERIZATION THEREWITH | ExxonMobil Chemical Patents Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| CN-102964371-B | A kind of preparation method of silicon bridge vicinal resistance type cyclopentadiene compounds | SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2015-08-12 | — | — | CN | disclosed |
| US-20140179884-A1 | Bridged Metallocene Compounds, Catalyst Systems and Processes for Polymerization Therewith | EXXONMOBIL CHEMICAL PATENTS INC. | 2014-06-26 | — | — | US | disclosed |
| WO-2014099303-A1 | BRIDGED METALLOCENE COMPOUNDS, CATALYST SYSTEMS AND PROCESSES FOR POLYMERIZATION THEREWITH | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-06-26 | — | — | WO | disclosed |
| CN-102257020-B | New metallocene compounds, catalysts comprising them, process for producing an olefin polymer by use of the catalysts, and olefin homo- and copolymers | LUMMUS NOVOLEN TECHNOLOGY GMBH | 2014-04-02 | — | — | CN | disclosed |
| CN-101889030-B | Metallocene compound, catalyst containing the same, and process for producing olefin polymer using the catalyst | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2013-07-17 | — | — | CN | disclosed |
| CN-103012623-A | Metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2013-04-03 | — | — | CN | disclosed |
| CN-102964371-A | Preparation method of silicon-bridged sterically-hindered cyclopentadiene compound | SHANGHAI RES INST CHEMICAL IND | 2013-03-13 | — | — | CN | disclosed |
| CN-101124252-B | Metallocene catalysts, their synthesis and use in olefin polymerization | NOVOLEN TECH HOLDINGS CV | 2011-10-05 | — | — | CN | disclosed |
| CN-101889030-A | Metallocene compound, catalyst containing the same, process for producing olefin polymer using the catalyst, and olefin homopolymer and copolymer | NOVOLEN TECH HOLDINGS CV | 2010-11-17 | — | — | CN | disclosed |
| CN-101341158-A | Cyclic cyclopentadienyl derivatives and process for preparing metallocenes from cyclic, substituted cyclopentadienyl derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-01-07 | — | — | CN | disclosed |
| CN-101124252-A | Metallocene catalysts, their synthesis and use in olefin polymerization | NOVOLEN TECH HOLDINGS CV (NL) | 2008-02-13 | — | — | CN | disclosed |
| EP-1052263-A2 | Transition-metal compounds, catalyst systems, process for their preparation and use in the polymerisation of olefins | TARGOR GmbH (DE) | 2000-11-15 | — | — | EP | disclosed |