Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | UGCG | Q16739 | 2/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3335357 | 1.00 | L3MBTL1 (0.50) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL22346842 | 0.87 | TSHR (0.54) | L3MBTL1TDP1TSHRNAAA | |
| SCHEMBL23227683 | 0.85 | TSHR (0.52) | L3MBTL1TDP1TSHRNAAA | |
| SCHEMBL4235184 | 0.85 | TSHR (0.48) | L3MBTL1TDP1TSHR | |
| SCHEMBL9011715 | 0.84 | TSHR (0.67) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL9011624 | 0.84 | TSHR (0.67) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL9011646 | 0.84 | TSHR (0.67) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL9011734 | 0.84 | TSHR (0.67) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL25195898 | 0.82 | TSHR (0.64) | L3MBTL1TDP1TSHRHRH4HRH3 | |
| SCHEMBL2640223 | 0.82 | TSHR (0.70) | L3MBTL1TDP1TSHRHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067625-B2 | Fluorosurfactants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-8049022-B2 | Fluorosurfactants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-11-01 | — | — | US | disclosed |
| US-20090312432-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20090264525-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312432-A1 | FLUOROSURFACTANTS | SGMS2, FASN, SGMS1 | L3MBTL1 3955/4885TDP1 4793/4885TSHR 1160/4885 |
| US-20090264525-A1 | FLUOROSURFACTANTS | FASN, FFAR3, SGMS2 | L3MBTL1 4360/4885TDP1 4827/4885TSHR 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.