Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.55 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8816235 | 0.99 | SLC9A1 (0.54) | SLC9A1SLC9A2HTR3EHTR3BHTR3A | |
| SCHEMBL9196979 | 0.88 | SLC9A1 (0.53) | SLC9A1SLC9A2AKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL8815995 | 0.87 | SLC9A1 (0.52) | SLC9A1SLC9A2AKR1C3AKR1C2 | |
| SCHEMBL8743846 | 0.85 | SLC9A1 (0.50) | SLC9A1SLC9A2 | |
| SCHEMBL7764005 | 0.85 | SLC9A1 (0.57) | SLC9A1 | |
| Hydrochloric Acid SCHEMBL8743834 | 0.84 | SLC9A1 (0.49) | SLC9A1SLC9A2 | |
| SCHEMBL9193762 | 0.82 | SLC9A1 (0.54) | SLC9A1SLC9A2 | |
| SCHEMBL8169691 | 0.81 | ADORA3 (0.47) | AKR1C3AKR1C2 | |
| SCHEMBL7768698 | 0.81 | — | — | |
| SCHEMBL8743817 | 0.81 | SLC9A1 (0.55) | SLC9A1SLC9A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114393-A | ADMINISTERING A BENZOYLGUANIDINE COMPOUND ANTIPROTOZOA AGENT | HOECHST MARION ROUSSEL DEUTSCHLAND GMBH (DE) | 2000-09-05 | — | — | US | claimed |
| EP-0901788-A2 | Use of inhibitors of the sodium hydrogen exchange in the manufacture of a medicament | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-03-17 | — | — | EP | claimed |
| US-6114393-A | ADMINISTERING A BENZOYLGUANIDINE COMPOUND ANTIPROTOZOA AGENT | HOECHST MARION ROUSSEL DEUTSCHLAND GMBH (DE) | 2000-09-05 | — | — | US | disclosed |
| EP-0901788-A2 | Use of inhibitors of the sodium hydrogen exchange in the manufacture of a medicament | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-03-17 | — | — | EP | disclosed |