Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL8169753

CCC(N)O.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.50

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Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.50
BLM P54132 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LAP3 P28838 5/20 0.48
METAP1 P53582 2/20 0.37
ANPEP P15144 4/20 0.34
ERAP1 Q9NZ08 1/20 0.34
SMPD1 P17405 2/20 0.33
ERAP2 Q6P179 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL183216 0.84 LAP3 (0.57) FDPSLAP3METAP1ANPEPERAP1
SCHEMBL5459578 0.83 TSHR (0.44) FDPSBLMTDP1LAP3
Phosphoric Acid SCHEMBL5462387 0.79 LAP3 (0.52) FDPSLAP3METAP1ANPEPERAP1
Pyrophosphoric Acid SCHEMBL27930355 0.79 FDPS (0.56) FDPSBLMTDP1LAP3ANPEP
Pyrophosphoric Acid SCHEMBL2426695 0.78 FDPS (0.71) FDPSBLMTDP1SMPD1
Pyrophosphoric Acid SCHEMBL5822274 0.78 FDPS (0.71) FDPSBLMTDP1SMPD1
Pyrophosphoric Acid SCHEMBL15065560 0.77 FDPS (0.53) FDPSBLMTDP1LAP3METAP1
Pyrophosphoric Acid SCHEMBL31072907 0.76 METAP1 (0.48) FDPSBLMTDP1LAP3METAP1
Pyrophosphoric Acid SCHEMBL28110229 0.75 FDPS (0.67) FDPSBLMTDP1LAP3SMPD1
Pyrophosphoric Acid SCHEMBL8761218 0.75 FDPS (0.67) FDPSBLMTDP1SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000074692-A1 A METHOD USING POTASSIUM DIHYDROGEN PHOSPHATE TO REDUCE CALCIFICATION OF TISSUE FREMANTLE HEART INSTITUTE PTY LTD (AU) 2000-12-14 WO disclosed