Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.70 |
| ▸ | HTR2C | P28335 | 5/20 | 0.70 |
| ▸ | HTR1A | P08908 | 4/20 | 0.70 |
| ▸ | HTR2A | P28223 | 4/20 | 0.70 |
| ▸ | HTR2B | P41595 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.70 |
| ▸ | BLM | P54132 | 3/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.70 |
| ▸ | HTR7 | P34969 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407437 | 1.00 | NPSR1 (0.70) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL818356 | 0.99 | NPSR1 (0.69) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL818357 | 0.99 | NPSR1 (0.69) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL10900004 | 0.92 | NPSR1 (0.63) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL6775810 | 0.89 | NPSR1 (0.72) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL471920 | 0.89 | NPSR1 (0.72) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL19357216 | 0.88 | HTR2C (0.76) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL5123328 | 0.88 | NPSR1 (0.70) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL471919 | 0.88 | NPSR1 (0.70) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL10900257 | 0.86 | NPSR1 (0.73) | NPSR1HTR2CHTR1AHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461289-B2 | Bioresorbable polymers synthesized from monomer analogs of natural metabolites | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-06-11 | — | — | US | disclosed |
| US-8415449-B2 | Bioresorbable polymers synthesized from monomer analogs of natural metabolites | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120302719-A1 | BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120197001-A1 | BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-08-02 | — | — | US | disclosed |
| EP-2459617-A1 | BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES | Rutgers, The State University of New Jersey (US) | 2012-06-06 | — | — | EP | disclosed |
| US-20110275782-A1 | BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-11-10 | — | — | US | disclosed |
| EP-2334712-A1 | BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES | Rutgers, The State University of New Jersey (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2011014858-A1 | BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-02-03 | — | — | WO | disclosed |
| WO-2010033640-A1 | BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-03-25 | — | — | WO | disclosed |
| CN-1861560-A | Carboxylic acid derivant, its preparation process and pharmaceutical composition | SHANGHAI PHARMACEUTICAL INST C (CN) | 2006-11-15 | — | — | CN | disclosed |
| EP-0701557-A4 | LAVENDAMYCIN ANALOGS, THEIR USE AND PREPARATION | BEHFOROUZ MOHAMMAD (US) | 1997-07-09 | — | — | EP | disclosed |
| EP-0701557-A1 | LAVENDAMYCIN ANALOGS, THEIR USE AND PREPARATION | BEHFOROUZ, Mohammad (US) | 1996-03-20 | — | — | EP | disclosed |
| EP-0498268-A2 | 5-Oxo-L-proline derivatives and pharmaceutical use thereof | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1992-08-12 | — | — | EP | disclosed |
| US-4908322-A | Reacting sample with O-acyl N-hydroxysulfosuccinamide to form N-acylated amine derivative, separating, chromatographically analyzing | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1990-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275782-A1 | BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES | BCAT2, WASF2, THEM6 | NPSR1 469/4885HTR2C 4445/4885HTR1A 4567/4885 |
| US-20120302719-A1 | BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES | BCAT2, WASF2, THEM6 | NPSR1 469/4885HTR2C 4445/4885HTR1A 4567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.