SCHEMBL8170508

SCHEMBL8170508

CO[Si](OC)(C1CC(C)CCC1C)C1CC(C)CCC1C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.30
TRPM8 Q7Z2W7 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6048945 0.88
SCHEMBL6048747 0.86
SCHEMBL6048941 0.83
SCHEMBL8165569 0.82 TRPA1 (0.30) TRPA1TRPM8
SCHEMBL4453761 0.81
SCHEMBL6048947 0.80
SCHEMBL7149890 0.80
SCHEMBL8624050 0.80
SCHEMBL6048850 0.76
SCHEMBL5419511 0.75 TRPM8 (0.52) TRPA1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6071846-A OLEFIN POLYMERIZATION CATALYST WHICH ALLOWS A POLYOLEFIN TO HAVE HIGH STEREOREGULARITY AND HIGH POLYMERIZATION ACTIVITY; SOLID TITANIUM CATALYST COMPONENT COMPRISES A MAGNESIUM ATOM, TITANIUM ATOM, HALOGEN ATOM AND ELECTRON DONOR TOKUYAMA CORPORATION (JP) 2000-06-06 US claimed
US-6071846-A OLEFIN POLYMERIZATION CATALYST WHICH ALLOWS A POLYOLEFIN TO HAVE HIGH STEREOREGULARITY AND HIGH POLYMERIZATION ACTIVITY; SOLID TITANIUM CATALYST COMPONENT COMPRISES A MAGNESIUM ATOM, TITANIUM ATOM, HALOGEN ATOM AND ELECTRON DONOR TOKUYAMA CORPORATION (JP) 2000-06-06 US disclosed
EP-0739907-B1 An olefin polymerization catalyst and a polyolefin production method TOKUYAMA CORP (JP) 1999-12-01 EP disclosed
EP-0739907-A1 An olefin polymerization catalyst and a polyolefin production method TOKUYAMA CORPORATION (JP) 1996-10-30 EP disclosed