Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817721 | 0.99 | TSHR (0.43) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL819049 | 0.95 | TSHR (0.42) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL819312 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNAESR1NPC1 | |
| SCHEMBL819019 | 0.83 | KDM4E (0.44) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL818056 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL818766 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL818677 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTCHRM2CHRM4 | |
| SCHEMBL818507 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL819151 | 0.76 | TSHR (0.48) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL818803 | 0.75 | TSHR (0.43) | ALDH1A1TSHRLMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |