SCHEMBL818677

SCHEMBL818677

CC(C)COC(=O)C1=C(C(=O)OCC(C)C)CCC(C)(C)C=C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM5 P08912 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
ADORA2B P29275 4/20 0.34
ADORA1 P30542 1/20 0.34
MAPT P10636 1/20 0.33
CACNA1F O60840 3/20 0.32
CACNA1D Q01668 3/20 0.32
CACNA1S Q13698 3/20 0.32
CACNA1C Q13936 3/20 0.32
MCL1 Q07820 1/20 0.32
JMJD6 Q6NYC1 1/20 0.32
PLA2G1B P04054 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32
P2RX4 Q99571 1/20 0.31
ALOX12 P18054 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819019 0.84 KDM4E (0.44) ALDH1A1TSHRCHRM2CHRM4CHRM5
SCHEMBL819312 0.81 ALDH1A1 (0.39) ALDH1A1TSHRCHRM2CHRM4CHRM5
SCHEMBL818056 0.80 ALDH1A1 (0.50) ALDH1A1TSHRMAPT
SCHEMBL819049 0.79 TSHR (0.42) ALDH1A1TSHRCHRM2CHRM4CHRM5
SCHEMBL817721 0.78 TSHR (0.43) ALDH1A1TSHRCHRM2CHRM4CHRM5
SCHEMBL817914 0.78 SLC6A2 (0.36) ALDH1A1ADORA2BMAPT
SCHEMBL818805 0.75 ALDH1A1 (0.45) ALDH1A1TSHRCHRM2CHRM4CHRM5
SCHEMBL817433 0.75 SLC6A3 (0.33)
SCHEMBL818057 0.74 ALDH1A1 (0.41) ALDH1A1TSHRCHRM2CHRM4CHRM5
SCHEMBL818466 0.70 ALDH1A1 (0.41) ALDH1A1TSHRCHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236908-B2 Components and catalysts for the polymerization of olefins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 US disclosed
US-20110269927-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed