Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.78 |
| ▸ | MYC | P01106 | 2/20 | 0.76 |
| ▸ | IL1RN | P18510 | 1/20 | 0.76 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.76 |
| ▸ | PNP | P00491 | 1/20 | 0.53 |
| ▸ | NAT1 | P18440 | 5/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.49 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.49 |
| ▸ | MAX | P61244 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172998 | 1.00 | TDP1 (0.78) | TDP1MYCIL1RNERAP1PNP | |
| SCHEMBL14860903 | 0.88 | TDP1 (1.00) | TDP1MYCIL1RNERAP1PNP | |
| SCHEMBL14860884 | 0.88 | TDP1 (1.00) | TDP1MYCIL1RNERAP1PNP | |
| SCHEMBL14860882 | 0.88 | TDP1 (1.00) | TDP1MYCIL1RNERAP1PNP | |
| SCHEMBL6962628 | 0.86 | MYC (1.00) | TDP1MYCIL1RNERAP1NAT1 | |
| SCHEMBL12961169 | 0.86 | MYC (1.00) | TDP1MYCIL1RNERAP1NAT1 | |
| SCHEMBL6962632 | 0.86 | MYC (1.00) | TDP1MYCIL1RNERAP1NAT1 | |
| SCHEMBL13388565 | 0.78 | INSR (0.80) | TDP1MYCIL1RNERAP1INSR | |
| SCHEMBL8177384 | 0.77 | GPR35 (0.66) | TDP1MYCIL1RNERAP1PTPN12 | |
| SCHEMBL8177382 | 0.77 | GPR35 (0.66) | TDP1MYCIL1RNERAP1PTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |