Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182662 | 0.87 | NR1H4 (0.41) | NR1H4GAAMAPTALDH1A1DPP4 | |
| SCHEMBL8187728 | 0.86 | NR1H4 (0.40) | NR1H4GAAMAPTALDH1A1DPP4 | |
| SCHEMBL8189247 | 0.85 | NR1H4 (0.42) | NR1H4GAAMAPTALDH1A1DPP4 | |
| SCHEMBL8188886 | 0.81 | KMT2A (0.44) | GAAMAPTALDH1A1TP53POLB | |
| SCHEMBL8182838 | 0.81 | NR1H4 (0.43) | NR1H4GAAMAPTMEN1KMT2A | |
| SCHEMBL8182302 | 0.80 | GAA (0.45) | GAAMAPTALDH1A1DPP4POLB | |
| SCHEMBL8182721 | 0.80 | CRHR1 (0.37) | GAAMAPTALDH1A1LCKDPP4 | |
| SCHEMBL8173105 | 0.78 | NR1H4 (0.39) | NR1H4GAAMAPTALDH1A1DPP4 | |
| SCHEMBL8189259 | 0.77 | NR1H4 (0.42) | NR1H4GAAMAPTALDH1A1PIK3CD | |
| SCHEMBL8172961 | 0.75 | KMT2A (0.40) | NR1H4MAPTALDH1A1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103736-A | SHOWING AN INHIBITORY ACTION ON GASTRIC ACID SECRETION AND A PROTECTIVE ACTION OF GASTRIC MUCOSA; 2-(HETERO)ARYL-3-AMINOIMIDAZO-(2,1-A)ISOQUINOLINES; ANTIULCER AGENTS; | SHINNIPPON PHARMACEUTICAL INC. (JP) | 2000-08-15 | — | — | US | disclosed |
| US-6020342-A | Fused imidazo[1,2-A]pyridines | SHINNIPPON PHARMACEUTICAL, INC. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0822194-A1 | FUSED IMIDAZO 1,2-a]PYRIDINES | Shinnippon Pharmaceutical Inc. (JP) | 1998-02-04 | — | — | EP | disclosed |